Diphenhydramine Hydrochloride 147-24-0     

Items
Specification
Results
Appearance
White or almost white crystalline powder
Complies
Solubility
Very soluble in water,freely soluble in alcohol
Complies
Identification
UV
Complies

IR
Complies

It responds to the tests for chloride
Complies
Melting range
168-172°C
168-169°C
Appearance of solution
Clear, NMTBY6
Complies
Acidity or alkalinity
NMT 0,5ml ofO.OlM NaOH
Complies
Related substance
Impurity A: 0.5% max
0.04%

Any other unspecified impurity: 0.3% max
Not Detected

Total impurities: 1.0% max
0.04%
Loss on drying
0.5% max
0.2%
Sulphated ash
0.1% max
0.04%
Assay(Dried substance)
99.0^101.0%
100.8%
Residual solvent 
Ethanol: 0.5% (5000ppm) max
0.03%

Toluene: 0.089% (890ppm) max
0.0004%

Function

1.Can eliminate all kinds of allergy symptoms.Its central inhibitory effect is significant, but not as good as         promethazine hydrochloride;Still have sedative.
2.Prevent dizzy move and antiemetic effect, also have fight choline effect.
3.Can alleviate bronchial smooth muscle spasm.For various allergic skin diseases, such as urticaria, insect bite. 4.Also used for motion sickness, nausea and vomiting.


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